Pepe’s Cantina Port St. Lucie

  4.7 – 1,212 reviews   • Mexican restaurant

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Pepe’s Cantina offers signature blend of authentic Mexican ingredients and innovative culinary techniques. Pepe and his team are ready to bring the best of Mexico right to your table! We promise you will love every bite. We invite you to come and enjoy a unique Mexican experience in a friendly and fun atmosphere!

✔️Brunch ✔️Lunch ✔️Dinner ✔️Dine in ✔️Take out ✔️Delivery Pepe’s Cantina Port St. Lucie 34986

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pepescantina.com

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Just a reminder: Today is Sunday Brunch. Join us from 11:30 AM to 3:00 PM for bottomless mimosas, plus a delicious upgrade to our brunch menu. Come try it! *Our …

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Reviews

Maya Porcelli
We had an incredible experience at Pepe’s Cantina in Port St. Lucie! From the moment we walked in, the atmosphere was beautiful, well-decorated, and full of great energy. The food was absolutely amazing, and the skinny margarita was perfectly refreshing.

The steak tacos were outstanding — full of flavor, incredibly tender, and honestly the best steak we’ve had locally. Every bite was delicious. The tableside guacamole is a must and added such a fun, fresh touch to the meal.

The staff was kind, attentive, and helpful, and our food came out quickly, which made the experience even better. Hands down, this is the best Mexican food in town, and we all agree it’s even better than one of our longtime favorites, Rocco’s Taco in Palm Beach Gardens.

We will absolutely be back and highly recommend Pepe’s Cantina to anyone looking for amazing food, drinks, and a great vibe!
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Foodie Queen
This place definitelty caught me by surprise. Being that I recently moved to the area , its hard sometimes to find somewhere that reminds me so much of south florida. The customer service was amazing , the food was delicious and the atmosphere was so fun and light.
EVERYTHING was fun and light. This has definitely become one of my favorite spots and I can see myself coming here all the time.

Hector – I dont know if he’s a manager or what but his customer service and hospitality was so amazing. We were shocked that good cust9mer service is still well and alive !!

Horchata Espresso Martini – 12/10
Mezcal Mule – 10/10
Sangria – 7/10
Piña Colada – 9/10

Chicken & Spinach – 10/10
Shrimp Tacos – 8/10
Fried pistachio ice cream- 10/10
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Cheryl Parker
First time coming while visiting my mom. Beautiful ambiance, staff was very attentive. Food was delicious. I had the grilled chicken bowl and my mom had steak fajitas. Drinks were tasty. Good portions. Highly recommended. Will come again when I visit.
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Tom O
Stopped into Pepe’s for Sunday Brunch and it is still top notch. They have been consistently excellent in food, service and atmosphere. Nicole was a wonderful server. She stopped by our table several times to check on us and see if we needed anything. She had great suggestions for meals and desserts. Very rare to sustain over a period of time. I still highly recommend this establishment.
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Patricia Harris
Everyone was so friendly. Our server Randy was amazing and very attentive. The table side guacamole is so good! The drinks were very good and strong. I had the grilled shrimp burrito was very good. The octopus was recommended by Randy and my husband really liked it. Didn’t have dessert but will the next time. Everything was really delicious and this is my favorite Mexican restaurant.
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Michael Stone
I had an outstanding experience at this restaurant. The food was absolutely delicious, and the service was commendable. However, I noticed that the server was a bit rushed and rushing me to order. Despite this minor inconvenience, I will definitely be returning to try out the rest of the menu. I highly recommend this place to anyone looking for a great dining experience to enjoy some excellent Mexican food.
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Matthew M.
The food. The drinks. The service.
Best Mexican restaurant in PSL!
If I’m being honest, it is a tad pricey. But if you want high end Mexican and an overall great experience, I highly recommend Pepe’s.
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D Tu
I’m not trying to be biased here because to be fair, I ordered takeout. However – before committing to trying a full entree, I wanted to test out two apps. For the price of these, ($10/each) I expected different. It did leave me feeling the integrity of the place ends when you order take out. The photos look amazing, and to my surprise this is what I pulled out of my bag. It was okay, didn’t taste bad or anything but now I’m not super invested. Hoping to give this place another chance, but for the price I spent, was it worth it? Not sure.

The chicharone serving was comical. They tasted good but would they really serve this in person? The plantain birria app was good, a new take on something. I can’t complain, but $10 for four plantains on a scoop of meat is wild.
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Chuck Whitty
My daughter gave my wife a gift certificate to Pepe’s Cantina for her birthday. We went there for dinner a few days ago. Afterwards I told my wife that, although I don’t eat Mexican food often, I’ve had plenty of experiences over the years and I cannot remember when I have had better tasting Mexican food. I was very impressed. From the taste of the salsa that accompanied the chips, to the tenderness of the steak in my Hawaiian Fajita, served in a hollowed out half of a pineapple. Our waitress, Laurie, was very nice and enhanced the experience, and the ambience of the restaurant is “fresh”. We had a great dinner and what we brought home in a box was enough to have another meal (ok, we are at the point of more like ‘senior portions’, but still…) I’m looking forward to going back!
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Elena J Sanchez
Everyone at Pepe’s was so friendly from start to finish! Our waiter, Daniel, went above and beyond—he kept checking in on us and made sure everything was perfect. The staff were all dressed so nicely and very professional.

And the food… absolutely incredible! Everything was so fresh, flavorful, and delicious. The gentleman who made our guacamole was super kind, and the guacamole itself was hands down the best we’ve ever had.

10/10 experience—thank you so much, Pepe’s! We’ll definitely be back next week. ✨
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