

Luisa’s Restaurant Wine Bar Since 1959 is a locally owned and operated Italian restaurant located in the heart of San Francisco, CA, offering a wide variety of delicious dishes to suit every taste. Our menu features classic Italian food, such as pizza, pasta, seafood, antipasti, and homemade pasta, all made with the freshest ingredients and prepared with care by our talented team of chefs. At Luisa’s Restaurant Wine Bar Since 1959, we believe that dining out should be an experience, which is why we also offer a wide selection of wine and create a warm and inviting atmosphere for you to enjoy.
Hours
| Friday | 5–11 PM |
| Saturday | 5–11 PM |
| Sunday | 5–10 PM |
| Monday | 5–10 PM |
| Tuesday | 5–10 PM |
| Wednesday | 5–10 PM |
| Thursday | 5–10 PM |
Address and Contact Information
Address: 1001 Guerrero St, San Francisco, CA 94110
Phone: (415) 800-7544
Website: https://italianrestaurantsanfrancisco.com/
Menu Photos
Order and Reservations
Reservations: opentable.com
italianrestaurantsanfrancisco.com
Photo Gallery
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Reviews
Gnocchi was some of the best I’ve had in a minute. Lobster ravioli was also really good. Pizza honestly didn’t look the most amazing but man it tasted great. Tiramisu was a little underwhelming but still tasty, just a tad bitter and wish they didn’t use Hershey’s.
Would come back for sure.
Amazing service, food and atmosphere. Good price!!
Luisa was there, and that was also incredible!
Will come back for sure!! LOVED IT
Luisa was at the restaurant greeting customers and watching over everything. She runs a tight ship, and the employees seem to adore her. I remember Luisa’s the restaurant when it was on Castro St. during the 80s. I always loved eating there. It was a joy to reminisce with her after all these years. And it’s amazing she is still going strong at 96!
Luisa’s Restaurant truly lives up to its reputation as a San Francisco gem. From the moment you step inside, you’re enveloped in an atmosphere that’s brimming with warmth, authenticity, and undeniable charm. It feels like walking into a beloved family home, filled with the aroma of incredible Italian cooking and the buzz of happy diners.
But the real highlight of my visit was getting to meet Luisa herself! She is an absolute delight – everything you’d expect from someone who has created such a remarkable establishment. Her passion and graciousness are palpable. She truly embodies the character of the place.
Speaking of highlights, I was incredibly fortunate to snag one of the bottles of wine that Luisa signed. It’s such a special keepsake and a testament to the personal touch that makes this restaurant so unique.
The food, of course, was fantastic. Every dish we tried showcased the freshest ingredients and the chefs’ clear passion for Italian cuisine. From the homemade pasta to the delicious pizza, it’s evident that every item on the menu is crafted with care.
Luisa’s isn’t just a meal; it’s an experience. It’s a place where you feel genuinely welcomed, where the food is incredible, and where the character of its owner shines through. I can’t recommend it highly enough!
Our waitress was lovely—genuinely kind and attentive, always greeting us with a smile and checking in at just the right moments. It was quiet for a Thursday evening, and we lucked out with a cozy window seat. Between the glow of the lights and our corner table banter, we probably looked like extras in a heartwarming movie about an old family-run trattoria.
The food? Solid. The cheesy pizza stole the show, but overall we weren’t floored. The meatball dish might deserve five stars on Yelp, but I’d call it a four-star Google Maps experience. Still, I’d definitely come back—especially with out-of-town guests who may prefer a more classic (and less chaotic) dining choice. I’ve got my eye on the carbonara next time.