Chemistry Chicago

  4.2 – 1,789 reviews   • Restaurant

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✔️Breakfast ✔️Brunch ✔️Lunch ✔️Dinner ✔️Dine in ✔️Take out ✔️Delivery Chemistry Chicago 60615

Hours

Monday6 PM–12 AM
Tuesday6 PM–12 AM
Wednesday6 PM–12 AM
Thursday6 PM–12 AM
FridayClosed
Saturday7 PM–12 AM
Sunday11 AM–3 PM, 5 PM–12 AM

Address and Contact Information

Address: 5121 S Harper Ave, Chicago, IL 60615

Phone: (773) 891-2106

Website: http://chemistrychicago.com/

Menu Photos

Order and Reservations

Reservations: opentable.com

chemistrychicago.com

Photo Gallery

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Reviews

Jamie Hasty
We enjoyed dinner for restaraunt week 2026. Portions were generous and the food was excellent! We each got and enjoyed a cocktail as well. The little popcorn they bring out to snack on is super delish! And everything came out super timely. They had live music as well and she was fun, talented, and super kind. The vibes were immaculate and so was the food. Plus I love supporting Black owned businesses year round, but I suppose its extra nice to do so during BHM. Can’t wait to go back! And YES there is free parking!! Kinda hard to find but once you do the exit from the lot is literally like 10 steps to the front of the restaraunt. Talk about chefs kiss!!
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Audrina Bovan
We came for my cousin’s birthday from out of town. BEST EXPERIENCE EVER!!! Our server Jerrard, aka Mr. Turn up, was AMAZING!! Everything he recommended was delicious! We loved absolutely everything we tried! He made my cousin’s birthday one we won’t forget! We’ll definitely be back!!!
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Booker T
My wife and I came from AL, to celebrate my Born Day, with my cousin and her husband. We had a great time. The music, atmosphere, service (from Evanye) and food (Tomahawk steak, mashed potatoes, cream corn, and Asparagus were “fye” ( for those that don’t know chicago language ). We will definitely be back.
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Tasia Conway (FEMALETWEETY)
Came here for restaurant week! The vibes/decor, live music and playlist (shoutout Cleo sol ), desserts and drinks were all delicious. The food however fell short (nothing seemed like it was seasoned unfortunately).

Food + desserts we tried:
-CRISPY SALMON STICKS
-WAGYU SMASH SLIDERS
-FAROE ISLAND MANGO JERK SALMON
-BANANAS FOSTER
-FRIED OREOS

Drinks we tried:
-AUTUMN ROSE
-MISSED CONNECTIONS

I honestly would only come back for the music and drinks, and I liked the concepts of having “getting to know your date” cards on the table and the waiters/waitresses dressed with lab coats as their blazers
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Sadé Greenidge
Had an incredible dinner with a friend here. Jessica was our server and gave us incredible recommendations. She was very attentive and kind as well. Highly recommend. They have a live dj on Wednesday nights too!!!
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Loucora Thomas
We had a ladies night here and this place did not disappoint! The food was , and portions were large. Prices are reasonable. I had lamb chops for my entrée which comes with mashed potatoes, then I added a side order of asparagus. My drink was delicious, I had a margaritas made with titos (I don’t do tequila. Waitress, Cheyenne, was awesome with managing our large group. I will be returning with the hubby!

Oh, reservations STRONGLY suggested!!
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James Hardrick
Nice high class restaurant. Great place to go for date night. Also had a live band playing. Food was fabulous. Reservations is adviced.
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Hannah Traywick
I visited here for my birthday dinner & the atmosphere/music is amazing! My dinner & mocktail was great but i will say i felt like service was slow. It took awhile for my server to come back to check on us. We ate here on a monday night so it wasn’t even that busy. Besides the “ok” service the food/drinks were amazing as well as the music & atmosphere!
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Stephanie Wedel
Cheyenne was amazing. She helped make my 43rd birthday so memorable. She was so helpful with recommendations ranging from drinks to apps to entrees. Will definitely be back.
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Whitney Nantista-Smith
Once we arrived in our Sprinter Van for our 8:15pm reservation we had to wait about 45 min. IT WAS FINE WITH US!!! They were cleaning up our area and finishing up last guests. From the minute we were greeted by RAY (MANAGER) and sweet curly haired receptionist we knew service would be great! We went on a Saturday 8/2/25. We were seated by 9pm, given our welcome to “Chemistry “ talk. Showed how to order in mini card. The server we had was a young light skinned man. He was amazing (can’t remember his name). He looked like a mini Mojo Brookz comedian lol. He was off the chain very thorough and knowledgeable. Took our order. By the time we came the nice RB set was ending and the DJ and crunk man came! Baby it turned into club vibes immediately!! The staff here loves their job. From the bus boys to the chef! Everyone was on 1 accord! We ordered got food and drinks. Food was amazing!!! They shouted out many people our FRIENDS BIRTHDAY AND HER BACHELORETTE PARTY WAS IN 1. We had a time!! For 10 women we paid about $800 plus our $160 reservation hold was deducted from our bill. Baby it’s worth every dollar! The chef here knows his business the steak melted in my mouth on my creamy Alfredo. The lamb chops are huge and the drinks are DRINKIN!!! Thanks RAY and staff for making our experience UNFORGETTABLE!!!! SUPPORT BLACK OWNED BUSINESSES.
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