Social Profile: 
![]()
✔️Brunch ✔️Lunch ✔️Dinner ✔️Dine in
… View more
Historic Main Street offers many unique shops and restaurants. Lewis & Clark’s offers wonderful space on three levels in a special turn of the century building. Wonderful House Dressing makes a great choice with our Salads. Hand breaded Shrimp, Peppered Filet with cognac sauce, Prime Rib and Fresh Salmon are all great choices.
Large, casual establishment with patio seating & a big American menu of steak, seafood & burgers.
Menu Photos
Photo Gallery
Related Web Results
Home – Lewis & Clark’s American Restaurant – Restaurant in St …
Lewis & Clark’s American Restaurant in St. Charles, MO. Call us at (636) 947-3334. Check out our location and hours, and latest menu with photos and …
Lewis & Clark’s | St. Charles MO – Facebook
Lewis & Clark’s, St. Charles. 5220 likes · 188 talking about this · 27963 were here. An American Restaurant and Public House…
Lewis & Clark’s Restaurant
Lewis & Clark’s Restaurant. Lewis & Clark’s Restaurant. 217 South Main Street. Saint Charles Missouri 63301. Food and Drinks. Information. Visit Website · Get …
Reviews
Gabi Barraza
I hardly give 5 star reviews, but the service was excellent, the food was great, and the view was amazing. We had mozzarella sticks, I ordered a Cesar salad, half a club, and green chili soup. This is a good spot for some comfort food, all very delicious. We sat outside on the patio and had a great fall view, and nice shops around to check out. Definitely recommend this place!
… moreGreg Heinz
We had a 19th birthday party for my granddaughter. TEN adults in attendance. They set us up in a side room, with only one other table, and it was empty. We ordered 3 appetizers. We had nachos & cheese, fried mushrooms and cheese sticks. They were massive, and extremely tasty (took some left-overs home). As you might guess, with 10 hungry people, and an extensive menu, we had quite a variety of entrees. I surveyed the group regarding their meals, and everyone was very complimentary of the food and the service. “Mary” was our server, and she was at-the-ready at all times. The entrée’s provided even more “To-Go” boxes. I’m sure many enjoyed some tasty left-overs the next day. We visited on MLK day, and the crowd was moderate. Traffic was light. Parking was very accessible, and everything about Lewis and Clark’s was top notch. HIGHLY RECOMMENDED
… moreJD (Badger)
From the moment we walked in, the atmosphere was warm and inviting — the perfect blend of cozy and upscale. We enjoyed a relaxed vibe, and the service was outstanding from start to finish.
But let’s talk about the food — absolutely phenomenal. Every dish was bursting with flavor and clearly made with fresh, high-quality ingredients. The presentation was beautiful, and you could tell a lot of care went into each plate. I highly recommend the spinach artichoke dip — it was easily one of the best things I’ve ever eaten.
This place is a gem, and I can’t wait to go back. Whether you’re here for a special occasion or just a great meal, you won’t be disappointed.
… moreBut let’s talk about the food — absolutely phenomenal. Every dish was bursting with flavor and clearly made with fresh, high-quality ingredients. The presentation was beautiful, and you could tell a lot of care went into each plate. I highly recommend the spinach artichoke dip — it was easily one of the best things I’ve ever eaten.
This place is a gem, and I can’t wait to go back. Whether you’re here for a special occasion or just a great meal, you won’t be disappointed.
LA LA The Clown
Great food, good flavor, soups of the day was broccoli and cheese, teriyaki chicken with pineapple had good flavor, the stuffed mushrooms were really good. And a very nice size. Not the usual very tiny stuffed mushrooms that I normally get at other places. The spinach artichoke dip what’s good on flavor, but the texture was a little crunchy for my taste. The spicy salmon was also very good, cooked well. Overall a good experience. I kept hearing some kind of rumbling noise, I was on the second story. Something in the restaurant was making a rumble sound. Other than that everything was great.
… morePaul Bonnette
I was looking for a late morning protein blast and stumbled in out of curiosity. This was some of my best stumbling, since the White chili was magnificent, the coffee tasty and the barkeep cute and pleasant. Main street St. Charles is a delight, as was this place!
… moreTerri Rudd
The whole place screamed other wordly elegance. The host and all staff treated you like a lost loved one coming home. So attentive and kind. Beautiful views throughout the whole place. Our waitress was so sweet explaining the many different food and drink options. The food!! The food was beyond amazing!! Nice size portions and I couldve made myself sick I couldn’t stop eating! Wanted to try everything on their menu. Definitely recommend!
… moreMyx Dóchasach
This place looks intriguing from the outside but is an absolute experience from the moment you hit the front doors. Cozy meets great views right off the cobblestone into this multistory restaurant. With a calm atmosphere their customer service really kicks it up a notch. Friendly, personable, and knowledgable staff really add to the experience. The food is sublime: the house salad has a parmesan vinagrette with fruity overtones, we ordered the fried catfish and chicken, which were well cooked and artfully presented. Our waiter kept up on our drinks and food throughout, without being overly present, was knowledgable about details of the food prep like the vinaigrette being a family recipe, and was honestly just a delight to interact with. From beginning to end a great experience.
… moreBianca Rogers
The catfish is incredible and a lot of food. Our server was amazing.
The bread service is amazing also! I highly recommend. This restaurant is surrounded by lots of fun shops, bakeries and coffee shops.
… moreThe bread service is amazing also! I highly recommend. This restaurant is surrounded by lots of fun shops, bakeries and coffee shops.
Lindsay B.
I don’t go to Old St. Charles often, but most of the times that I have, I’ve eaten at Lewis and Clark’s. Their food is SO GOOD, and the interior of the restaurant is very comfortable. I went with my mom, my daughters, and one of their friends, and it was just as expected. I had the glazed salmon sandwich with fries (literally the best fries I’ve ever had) and it was delicious. Everyone loved their meals and afterwards we were nice and full and ready to go browse some shops!
… moreSandie-Leigh Edwards
Great historical vibe. Great food and service especially from our server Mary, made our first night visiting from Australia, just awesome.
… more