Piacere Mio Uptown

  4.9 – 67 reviews   • Italian restaurant

At Piacere Mio we believe in crafting more than meals — we create memories. Inspired by the vibrant regions of Italy (with a special nod to Sicily) and led by Chef Jose Marquez and owners Antonio de la Rosa and Francisco Perez, we bring warm hospitality, house-made pasta, and authentic flavors together under one roof. Whether it’s your first visit or your hundredth, our goal is simple: you feel like you belong, your food feels like home, and you leave with a smile.

✔️Dinner ✔️Dine in ✔️Take out Piacere Mio Uptown 60640

Address and Contact Information

Address: 1303 W Wilson Ave, Chicago, IL 60640

Phone: (872) 302-4162

Website: http://piaceremiouptown.com/

Menu Photos

Order and Reservations

Reservations: opentable.com

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Reviews

Janelle Iaccino
I have eaten all over Italy and have to start by saying this was one of the best Italian meals I have had in the U.S. I’ve lived in Uptown for 15 years. We have needed a restaurant like this to open for years.
The quality of the ingredients are evident in the flavors of their thoughtfully curated dishes, not in the price.
The wine list has all the best picks to pair with their specials. Half price bottle Mondays are the perfect way to start the week.
Alfredo and Antonio are incredibly attentive and charismatic. They take pride in delivering an authentic and enjoyable experience. You feel it with every visit to the table.
I had the zucchini flowers, beetroot salad, short ribs and mascarpone cream chocolate shell dessert. Every bite was amazing. I can’t wait to go back to try other menu items!
I highly recommend this intimate spot for a date night, girl hangs, and solo indulgence!!!
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Clay Goldman
We came to Piacere Mio for our Valentine’s Day dinner after seeing comments about how well they handled celiac and gluten-free food. I have nothing but praise for our experience.

Food-wise, everything was delicious. The grilled octopus was the perfect starter followed by some delicious pasta. For dessert, I went with a tiramisu, which was splendid.

Our waiter was great. He was super knowledgeable about the kitchen precautions and made us feel very safe about potential cross-contact.

As to the vibe, it’s a very cute restaurant. The smaller interior makes it feel intimate without losing the charm of a nice Italian restaurant.

Overall, we had a fantastic time. If you have the opportunity to come to Piacere Mio, you should take it.
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Brian Dodds
Fantastic meal at Piacere Mio! The food was excellent, especially the cacio e pepe and fettuccini nero with seafood. Great service and staff recommendations too. Highly recommend for a date night or larger gatherings!
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Eddie Gonzalez Fuentes
Incredible experience!! Probably the best Italian restaurant in the city. The food is amazing, the service is impeccable. And don’t forget to try the desserts with the pistachio liqueur shot – unbeatable! We can’t wait to go back!
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Vasil Lalov
We are so excited and happy that Piacere Mio is open in Uptown. The food is great, well priced and the atmosphere is welcoming. We will continue coming to this place to try new items on the menu and we can’t wait to see what they do with the garden area in the summer!
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Steven Ingram
⭐️⭐️⭐️⭐️⭐️ A Must-Try New Italian Gem in Uptown!

I’m officially the first customer of this brand-new Italian restaurant that opened today, November 24, 2025, right across the street from my home in Uptown. I can already tell this place is going to become a neighborhood favorite very quickly.

Every patron I spoke with was blown away by their meal. People were describing their entrées with words like unbelievable, amazing, and you have to try this. That kind of feedback tells you the food is something special.

I ordered the short rib entrée, and it was absolutely divine. The meat melted in my mouth and was prepared perfectly. As I waited, Francisco, the owner, offered me a complimentary glass of wine. He was warm, attentive, and genuinely excited to bring great Italian food to our community.

I live right across the street, and I already know I will be coming back often. There are so many other entrées on the menu that I cannot wait to try. Uptown truly gained a fantastic addition today.

If you are in the neighborhood, treat yourself to this place. You will not be disappointed, and you might discover your new favorite spot.
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Isabelle Muthiah
Probably my favorite Italian food I’ve had in this city. Delicious sea food, great drinks. 10/10
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Steven Betancourt
This place is hot right out the gate. An easy to converse ambiance. A hot wine hot list and a solid menu. Impeccable service and food that makes you want to come back every day. Pictures are Cacio Pepe and the seared tuna. If you are in doubt, knock it off, get your butt here.
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ana maria moya cendales
This place is wonderful! The food is absolutely amazing and delicious, the experience with the wine and the outstanding service makes you feel absolutely comfortable. I really enjoy my birthday there! The desserts were incredible by the way!
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Bryan Iadisernia
As soon as you walk through the door you’re greeted with very friendly service. The food is delicious, the atmosphere is warm and cozy, and staff is very attentive and caring. Cannot recommend this place enough!
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